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There are many approaches which are employed to enhance the skin permeation rate of active moieties. Investigation of the anti-inflammatory potential of Aloe vera gel NIL Source of Support. These data suggest that specific plant sterols may also contribute to the anti-inflammatory activity of Aloe Vera Gel [12]. Aloe Vera Gel consists primarily of water and polysaccharides pectins, hemicelluloses, glucomannan, acemannan, and mannose derivatives. Comparative depth profiling and metabolism of eicosapentaenoic acid.

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Some constituents of the A. Alternative routes of drug administration such as the transdermal route are less desirable and feasible compare to the most convenient drug intake methods i. Burn treatment Aloe Vera Gel has been used for the treatment of radiation burns. Clinical investigations suggest that Aloe Vera Gel preparations accelerate wound healing. As mentioned before, this discrepancy in polysaccharide composition was initially explained by differences in geographical locations of the plants and seasonal changes but later it was found that extraction and processing of the parenchyma tissue are also very important variables that contribute to the differences in the results.

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Aloe Vera Gel has been used for the treatment of radiation burns. NIL Source of Support. It has been hypothesized that this heterogenous composition of the Aloe vera pulp may contribute to the diverse pharmacological and therapeutic activities which have been observed for aloe gel products. Transdermal delivery of drugs promises many advantages over oral or intravenous administration, though human skin provides an effective barrier to the permeation of most drugs in the form of stratum corneum. Lupeol, salicylic acid, urea nitrogen, cinnamonic acid, phenols and sulfur. Although it was claimed that some of the biological activities of this plant can be attributed to the polysaccharides found in the leaf gel, it is a daunting task to link individual polysaccharides to specific therapeutic properties.

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Description: It is not a cactus, but a member of the tree lily family. Antiviral and antitumor activity. Gums and mucilages from natural origin that contain complex polysaccharides have found a wide range of pharmaceutical applications such as functional excipients in dosage forms, which include binders, disintegrants, emulsifiers, suspending agents, gelling agents and sustaining agents in modified release tablets. Fresh Aloe Vera Gel significantly reduced acute inflammation in rats carrageenininduced paw oedema , although no effect on chronic inflammation was observed. Anthraquinones present in latex are a potent laxative. Effects on skin exposure to UV and gamma radiation. A drug for all seasons.
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